That’s 20 to 30 genes per novel, and genes are way way shorter than the information equivalent of 5,000 words (150 thousand divided by 30).
And CRISPER goes after them one at a time.
Not only that, but many genes have multiple roles. Genes adjust and serve multiple non-interacting usages. They get to the point in some awkward, haphazard ways, which is what you might anticipate after half a billion years of trial-and-error with only “it works!” as your guide.
Love the thought, but that level of control is still far far into the future.